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Exponent Staff Publish Article on Infant Formula and Probiotics


March 7, 2012

Drs. Dominik Alexander and Vanessa Perez in the Center for Biostatistics, Epidemiology, and Computational Biology in the Chicago office have had their recent work published in the January 2012 issue of the Journal of Parenteral and Enteral Nutrition.

The study entitled, “Bifidobacterium lactis Bb12 enhances intestinal antibody response in formula-fed infants: a randomized, double-blind, controlled trial,” followed 6-week old healthy full-term infants for 6 weeks to examine the effect of infant starter formula containing the probiotic Bifidobacterium animalis subspecies lactis (Bb12) on intestinal immunity and inflammation. The research compared 2 groups randomized to partially hydrolyzed whey formula or the same formula containing Bb12 in parallel to a breastfed comparison group. The findings indicated that negative immune-related effects of not breastfeeding and cesarean delivery are potentially mitigated with the inclusion of Bb12 in infant formula, therefore providing infants a safe, dietary, immune-modulating bacterial introduction. This work was supported by Nestle Infant Nutrition.