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Stem Cell-based Tissue Engineering and Regenerative Medicine Therapies


February 1, 2010

Stem cell-based tissue engineering and regenerative medicine therapies pose a promising treatment option for repairing a variety of pathological conditions and injuries. A recent story published online in the January 19, 2010 Early Edition of the Proceedings of the National Academy of Sciences of the United States of America (PNAS) highlights the work of Exponent Associate Kenneth Dupont (Biomechanics, Philadelphia), whose research showed the ability of stem cells to enhance the repair of large bone defects in rats compared to treatment with a comparable acellular therapy. These results show the potential for future clinical stem cell therapies to treat patients who have lost large amounts of bone, such as those who have experienced trauma resulting from serious injury and those who have lost bone during tumor resection. Mr. Dupont’s research was performed at the Georgia Institute of Technology’s Institute for Bioengineering and Biosciences under the advisement of Institute director Dr. Robert Guldberg.