Ms. Shirley has 18 years of experience assisting on human health and ecological risk assessments. In this context, she has conducted extensive data management and analysis; prepared spreadsheets for exposure assessment, conducted literature researches, and designed and managed databases of both environmental data and historical documents. She has performed calculations for human health and ecological risk assessments involving a wide range of chemicals and exposure situations.
In support of clients in litigation, Ms. Shirley has conducted file reviews and prepared case summaries, prepared exhibits and reports, and managed large groups of staff in data management and file review projects. She is proficient in Word, Excel, and Access.
Kaetzel RS, Yost LJ, O’Boyle RA, Shirley CH, Booth PN. Predictive human health risk assessment for a new aluminum smelter in Iceland. Poster at the 46th Society of Toxicology Annual Meeting, Charlotte, NC, March 27, 2007.
AsbestosPrepared case summaries for 40 separate asbestos litigation cases over the past 4 years, all involving individuals with health effects such as mesothelioma, asbestosis, lung cancer, or other respiratory ailments.
Conducted detailed reviews of documents for an asbestos litigation case.
Human Health Risk AssessmentConducted toxicological screenings and calculated risk estimates used in the development of work plans and multipathway risk assessments where the primary issue was exposure to PCDD/Fs in soil and in a river food chain environment.
Conducted toxicological screenings and calculated risk estimates used in the evaluation of potential health risks related to fugitive dust along an ore haul road and port facility in northwest Alaska and community concerns about risks from subsistence foods and adverse effects to the environment.
Conducted toxicological screenings and calculated risk estimates for human health risk assessments to evaluate potential effects of mercury and PCBs in sediments, water, and fish in an urban lake in New York State. Participated in data analysis conducted in support of remediation at the site.
Conducted toxicological screenings and calculated risk estimates for a human health risk assessment at a superfund site in New Jersey (a landfill associated with a former mercury processing facility), where the primary contaminant was mercury in soil and groundwater.
Conducted toxicological screenings and calculated risk estimates for human health risk evaluations and pathway analyses in support of an evaluation of costs and benefits of bioremediation of PCP-contaminated soil versus excavation and disposal at former wood treating facilities on the West Coast.
Managed a database of air modeling data for more than 10,000 receptor points under 99 discrete simulation scenarios to support the risk assessment for a site in Iceland.
Litigation SupportLed project teams of data entry personnel for an agricultural-based litigation project involving multiple defendant teams, regarding current agricultural waste management practices.
Provided litigation support for a site in the eastern United States. Reviewed 10 years of historical indus¬trial plant records and prepared spreadsheets summa¬rizing volumes of products, raw materials, and waste streams.
Provided litigation support for a site in the Midwest. Managed and organized discovery materials and data for the project manager.
Created trial exhibits for an NRD case in the western United States.
Natural Resource Damage AssessmentConducted an onsite review of historical industrial plant records for sites involved in a large natural resource damages claim in the Midwest. Coordinated compilation of a bibliographic database of those historical industrial plant records and environmental documents. Reviewed, coded, and entered more than 3,700 bibliographic records into electronic library resource. Participated in regular project meetings with the client and other subcontractors and prepared meeting minutes.
Tracked costs for remediation projects. Prepared semiannual reports for submittal to the Trustees and other parties.
Conducted a review of historical documents to identify data to be used in evaluation of an NRD project on a river in upstate New York. Reviewed data entry for accuracy and completeness, and prepared summaries for the Trustees. Managed the document database for the site. Participated in data analysis and supported GIS activities.
Product SafetyAssisted in evaluating and compiling data from metabolism, toxicokinetic, and toxicity papers and reports for four draft safety assessments that were prepared for a fragrance industry expert panel’s review and publication. Publicly available information, published papers, and industry-sponsored reports included the following study types: acute toxicity, repeat-dose toxicity, carcinogenicity, reproductive and developmental toxicity, irritation, sensitization, phototoxicity, and photoallergenicity. In all, more than 2,100 documents were reviewed.
Assisted in comparison of the endpoints of toxicity for 16 herbicides that have been re-registered since 1997, to determine the scientific value of toxicity testing conducted by the registrant of each herbicide. Information regarding special review, need for new studies, high volume use, special aggregate or cumulative risk assessments, human epidemiology, endocrine disruption, reproductive toxicity, neurological toxicity, developmental toxicity, carcinogenesis, irritation or sensitization, groundwater or surface water concerns, and ecotoxicity were tabulated for each herbicide.
Assisted in compilation of NOAEL values and the effects seen at the LOAEL on 57 pesticides for developmental, reproductive, and developmental neurotoxicity studies. The factors used in the risk assessment for registration eligibility decisions were compared to better understand the dynamics of what to test.
Assisted with the compilation of effects levels for different endocrine sensitive endpoints in historical and current toxicology studies of 2,4-D. These data were summarized and presented to EPA’s endocrine disruptor screening program (EDSP) to negotiate extent of further Tier 1 or Tier 2 toxicity testing.
OtherParticipated in an onsite review of employee records for cohort enumeration at a TCE site in Oregon.
Prepared a database for evaluation of sediment quality guidelines for the ecological evaluation of a river in New York State.
Tracked samples from field collection to the laboratory and from the laboratory to the data report for a fast-tracked RI/FS in Oklahoma. Activities involved daily monitoring of sample status, advising project management on progress of sample analysis and data review, and reviewing subcontractor invoices.
Operated a sample tracking system to monitor the status of more than 3,500 samples for an RI/FS in New York State. Activities involved tracking of laboratory data packages, comparing results to the work plan, final review¬ing of data tables and quality validation reports, and reviewing subcontractor invoices. Also tracked and reported the status of all data validation reports and SOPs associated with the RI/FS data reports. This included more than 100 different individual documents with different authors, review¬ers, and editors.