Colleen Kelly, Ph.D.

Dr. Kelly's research is primarily focused in biostatistics, developing statistical methodology to address biological and medical problems. She has developed and evaluated methodology for identifying drug interactions, and analyzing data from clinical trials and epidemiological, ecological, and behavioral studies. She has also worked in the area of modeling molecular evolution.

Dr. Kelly has experience in statistical consulting and data analysis for observational studies, experiments, and sample surveys. She has designed studies, analyzed data, written statistical analysis plans and reports in the pharmaceutical, vaccine and medical device arenas. She has served as an expert witness in civil cases involving construction defects, medical devices, intellectual property, antitrust and employee compensation.

As a tenured associate professor of statistics at San Diego State University, Dr. Kelly co-founded and co-directed the university’s statistical consulting center. Prior to joining Exponent, she served as the consulting statistician at Victoria University in Wellington, New Zealand.

Wiener GJ, Tsukashima R, Kelly C, Wolf E, Schmeltzer M, Bankert C, Fisk L, Vaezi M. Dx-pH Measurement SystemTM: In search of a sensitive device for detecting liquid and aerosolized supraesophageal gastric reflux. J Voice 2008; in press. DOI: 10.1016/j.jvoice.2007.12.005.

Kelly C, Arnold R, Galloway Y, O’Hallahan J. The authors reply. American Journal of Epidemiology 2008; doi: 10.1093/aje/kwn050.

Ray R, Ketcham B, Huang S-W, Kelly C. Fire in large truck crashes: Comparing results from the Large Truck Crash Causation Study with FARS and NASS/GES data. SAE 2008-02-0255.

Wilmes A, Bargh K, Kelly C, Northcote P, Miller J. Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines. Molecular Pharmaceutics 2007; 4(2):269–280.

Kelly C, Arnold R, Galloway Y, O’Hallahan, J. A prospective study of the effectiveness of the New Zealand meningococcal B vaccine (MeNZBTM). American Journal of Epidemiology 2007; 166(7):817–823.

Chia S, Weisman RA, Tieu D, Kelly C, Dillmann WH, Orloff LA. Prospective study of perioperative factors predicting hypocalcemia after thyroid and parathyroid surgery. Archives of Otolaryngology – Head & Neck Surgery 2006; 132(1):41–45.

Kelly C, Price T. Correcting for regression to the mean in behavior and ecology. American Naturalist 2005; 166(6):700–707.

Kelly C, Rao-Melacini P, Zhao W. Using James-Stein estimators in tests of homogeneity of the risk difference. Communications in Statistics – Simulation and Computation 2005; 34(1):41–55.

Feng P, Kelly C. An extension of the Model-Free Test to test synergy in multiple drug combinations. Biometrical Journal 2004; 3:293–304.

Romano TA, Keogh MJ, Kelly C, Feng P, Berk L, Schlundt CE, Carder DA, Finneran J. Anthropogenic sound and marine mammal health: Measures of the nervous and immune systems before and after sound loud enough to shift hearing threshold. Canadian Journal of Fisheries and Aquatic Sciences 2004; 61:1124–1134.

Kelly C, Price T. Comparative methods based on species mean values. Mathematical Biosciences 2004: 187(2):135–154.

Smith J, Kelly C. Stylistic constancy and change across literary corpora: Using measures of lexical richness to date works. Computers and the Humanities 2002; 36(4):411–430.

Lui K.-J, Kelly C. Tests for homogeneity of the risk ratio in a series of 2x2 tables. Statistics in Medicine 2000; 19(21):2919–2932.

Castillo EM, Rickman LS, Ledbetter EL, Kelly C. Streptococcus Pneumoniae bacteremia in an era of penicillin resistance. American Journal of Infection Control 2000; 28(3):239–243.

Lui K.-J, Kelly C. A revisit of tests for homogeneity of the risk difference. Biometrics 2000; 56:309–315.

Kelly C, Lake S, Mather T. Estimation of the transmission probability of Lyme borreliosis. Biometrical Journal 1999; 41(6):1–17.

Lui K.-J, Kelly C. A note on interval estimation of kappa in a series of 2x2 tables. Statistics in Medicine 1999; 18:2041–2049.

Kelly C, Kammann E, Bak J, Mather T. An improved method for predicting duration of black-legged tick (Ixodes scapularis) attachment. Systematic and Applied Acarology 1999; 4:31–38.

Legare ML, Eddleman WR, Buckley PA, Kelly C. The effectiveness of tape playback in estimating Black Rail density. Journal of Wildlife Management 1999; 63(1):116–125.

Hu R, Markowski D, Hyland K, Kelly C, Mather T. Human Infection with tick-transmitted Babesia microti in Rhode Island: Serological evidence and risk factor assessment. Journal of Spirochetal and Tick-borne Diseases 1996; 3(3):135–139.

Kelly C, Churchill G. Biases in amino acid replacement matrices and alignment scores due to rate heterogeneity. Journal of Computational Biology 1996; 3(2):307–318.

Kelly C, Rice J. Modeling nucleotide evolution: A heterogeneous rate analysis. Mathematical Biosciences 1996; 133:85–109.

Yeh M.-T, Bak JM, Hu R, Nicholson M, Kelly C, Mather T. Determining the duration of Ixodes scapularis attachment to tick-bite victims, Journal of Medical Entomology 1995; 32(6):853–858.

Kelly C. A test of the Markovian model of DNA evolution. Biometrics 1994; 50:653–664.

Kelly C, Rice J. Monotone smoothing and its applications to dose-response curves and the assessment of synergy. Biometrics 1990; 46:1071–1085.

Goel R, Cleary SM, Horton C, Kirmani S, Abramson I, Kelly C, Howell SB. Effect of sodium thiosulfate on the pharmacokinetics and toxicity of cisplatin. Journal of the National Cancer Institute 1989; 81(20):1552–156

Published Presentation Proceedings

Miller J, Wilmes A, Bargh K, Kelly C, Northcote P. Peloruside A and paclitaxel synergise in their cytotoxic and microtubule-stabilizing effects in cultured cancer cell lines. 97th Annual Meeting of the American Association for Cancer Research 2006, Washington D.C., April 1–4, 2006.

Wiener GJ, Bankert C, Kelly C, Fisk CL, Schmeltzer M, Wolf E, Tsukashima R. Dx-1: A new device for detecting supraesophageal gastric reflux (SEGR). American College of Gastroenterology's 70th Annual Meeting, Honolulu, Hawaii (abstract), 2005.

Oechel WC, DeRoma D, Ross D, Taylor N, Kelly C, Verfaillie J. Using near-real-time data in K-6 educational outreach. American Meteorological Society’s 14th Symposium on Education (abstract), 2004.

Lo K, Kelly C. A bootstrap test for homogeneity of risk differences in a matched-pairs, multi-center design. Proceedings, American Statistical Association, Biopharmaceutical Section, Toronto, Canada, 2004.

Rao-Melacini P, Kelly C. The use of James-Stein estimators in tests of homogeneity of the risk difference. Proceedings, American Statistical Association, Biopharmaceutical Section, Toronto, Canada, 2004.

Feng P, Kelly C. An extension of the MFT to test synergy in multiple drug combinations. Proceedings, American Statistical Association, Biometrics Section, San Francisco, CA, 2003.

Kelly C, Kawashima T, Feng P. An improved Model-Free Test of synergy in drug combinations. Proceedings, American Statistical Association, Biometrics Section, San Francisco, CA, 2003.

Kelly C. Heterogeneous rate models of DNA evolution. Proceedings, American Statistical Association, Biometrics Section, Chicago, IL, pp. 189–193, 1996.

• Consulting Statistician, Department of Mathematics, Computer Science and Statistics, Victoria University of Wellington, New Zealand, 2005–2007
• Associate Professor, Department of Mathematics and Statistics, San Diego State University, 1997–2005
• Adjunct Associate Professor, Graduate School of Public Health, San Diego State University, 1998–2005
• Assistant Professor, Department of Computer Sciences and Statistics, University of Rhode Island, 1991–1997