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Dr. Heilman's expertise includes in vitro and animal models of toxicity, mechanistic and chemical toxicology, and pulmonary injury and disease. She currently conducts safety assessments and toxicology reviews for a variety of compounds in food, consumer products, and environmental media. She also composes written scientific analyses and performs literature review. Prior to joining Exponent, Dr. Heilman conducted research for over 7 years in a variety of disciplines including pulmonary radiation injury, cigarette smoke-induced pulmonary toxicity, antioxidant modulation of lung cancer and inflammatory pathways, and DNA site-selectivity of nitrosamine carcinogens. Dr. Heilman has expertise in a variety of techniques and approaches from analytical chemistry to mouse models of disease. Her credentials manifest a broad training in academic coursework and experimental research.
Watson WH, Heilman JM, Hughes LL, Spielberger JC. Thioredoxin reductase-1 knock down does not result in thioredoxin-1 oxidation. Biochemical and Biophysical Research Communications 2008 Apr; 68(3):832–836.
Lu X, Heilman JM, Blans P, Fishbein JC. The structure of DNA dictates purine atom site selectivity in alkylation by primary diazonium ions. Chemical Research in Toxicology 2005 Sep; 18(9):1462–1470.
Selected Presentations and Published Abstracts
Heilman JM. Thioredoxin reductase depletion inhibits NFB in a thioredoxin independent manner. Poster, Society of Toxicology Annual Meeting, 2009.
Heilman JM. Thioredoxin reductase activity modulates NFB-signaling at the nuclear compartment. Poster, American Association for Cancer Research Annual Meeting, 2008.
Heilman JM. Thioredoxin reductase is required for maximal NFB-mediated gene expression. Poster, Society of Toxicology Annual Meeting, 2007.
- Post-Doctoral Fellow, Laboratory of Shyam Biswal, Ph.D., Johns Hopkins University, Bloomberg School of Public Health, 2009–2010
- Graduate Research Assistant, Laboratory of Walter H. Watson, Ph.D., Johns Hopkins University, Bloomberg School of Public Health, 2004–2009
- Teaching Assistant, graduate course in Terrorism and Public Health, Johns Hopkins University, Bloomberg School of Public Health, 2005–2006
- Undergraduate Research Assistant, Laboratory of James C. Fishbein, Ph.D., University of Maryland, Baltimore County, 2003–2004
Provided toxicology review and support for Generally Recognized as Safe (GRAS) dossiers. Conducted toxicological literature search and data review to support pesticide registrations. Performed toxicology reviews and conducted risk assessments for children’s toys. Reviewed dietary and nutrition literature to evaluate potential for health effects of a food in a susceptible subpopulation.
- American Chemical Society, 2003–2005
- Society of Toxicology, 2007–present
- American Public Health Association, 2010–present
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- Ph.D., Environmental Health Sciences, Johns Hopkins University, 2009
- B.S., Chemistry, University of Maryland, Baltimore County, 2004
- NIEHS Post-doctoral Training Grant Fellow, 2009–2010
- NIEHS Pre-doctoral Trainee, 2004–2009
- Certificate in Risk Sciences and Public Policy, Johns Hopkins University, Bloomberg School of Public Health, 2008
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