Peng-Meng Kou
Peng-Meng Kou, Ph.D.
Manager
Polymer Science & Materials Chemistry
  • Natick

Dr. Kou specializes in the areas of medical device and pharmaceuticals, with emphasis on design review and failure analysis of medical device, pharmaceuticals, and drug/device combination products. Dr. Kou assists clients in product development and manufacturing, clinical trial support, FDA submissions, API assessment and characterization, product launch, and post-market surveillance. Dr. Kou has also applied her technical skills to other industries, including high value manufacturing of consumer electronics and consumer products. She also has experience supporting technology due diligence pertaining to mergers and acquisitions associated with biomaterials, high performance polymers, and sports equipment companies.

Dr. Kou has extensive knowledge in biomedical material characterization and host/device interactions. Her material characterization experience includes X-ray photoelectron (XPS), scanning electron microscopy (SEM), optical profilometry, 3-D confocal microscopy, H-NMR, mass spectrometry, time-of-flight secondary ion mass spectrometry (ToF-SIMS), endotoxin detection, and cytotoxicity of materials. Dr. Kou has considerable experience in characterizing human immune cell response to dental titanium implants and polymeric biomaterials, including optical, fluorescent, and confocal microscopy, flow cytometry, immunochemistry, high-throughput cell-based assay development, human blood immune cell and cell-line culture, DNA transfection and transduction of cells, multiplex protein and DNA quantification, and cryopreservation of cells. She is also knowledgeable with microfabrication of silicon biosensing devices and is familiar with inorganic and organic clean room environments.

Prior to joining Exponent, Dr. Kou was a research assistant in the Department of Biomedical Engineering at the Georgia Institute of Technology, where she studied correlations between biomaterial properties and human dendritic cell (an important immune cell type) response. She developed a high-throughput analysis platform to study dendritic cell/biomaterial interactions and created a statistical model to predict immune cell response from material properties.

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Bioengineering, Georgia Institute of Technology (Georgia Tech), 2011
  • B.S., Biological and Environmental Engineering, Cornell University, 2005, magna cum laude
  • Nerem Travel Award for International Collaboration, Georgia Institute of Technology, 2008

    International Student Scholarship, Cornell University, 2003–2005

    Undergraduate Research Award, Cornell University, 2004–2005

    Undergraduate Achievement Award, American Chemical Society, 2003

LICENSES & CERTIFICATIONS

ISO 13485 Medical Device Quality Management Systems Internal Auditor

PADI Advanced Open Water Diver

PADI Enriched Air Diver

LANGUAGES

  • Cantonese Chinese
  • Mandarin Chinese

Publications

Kou P, Clevenger J. A Coat for all weathers: The hydrophilic coatings market. MedicalDevice-Network.com, May 31, 2012.

Kou P, Pallassana N, Bowden R, Cunningham B, Joy A, Kohn J, Babensee JE. Predicting biomaterial property-dendritic cell phenotype relationships from multivariate analysis of responses to polymethacrylates. Biomaterials 2012; 33:1699–1713.

Kou PM, Schwartz Z, Boyan BD, Babensee JE. Dendritic cell responses to surface properties of clinical titanium substrates. Acta Biomaterialia 2011; 7:1354–1363.

Kou PM and Babensee JE. Macrophage and dendritic cell phenotypic diversity in the context of biomaterials. Journal of Biomedical Materials Research A 2011; 96:239–260.

Kou PM and Babensee JE. Validation of a high-throughput methodology to assess the effects of biomaterials on dendritic cell phenotype. Acta Biomaterialia 2010; 6:2621–2630.

DeLouise L, Kou PM, Miller BL. Cross-correlation of optical microcavity biosensor response with immobilized enzyme activity: Insights into biosensor sensitivity. Analytical Chemistry 2005; 77: 3222–3230.
Presentations

Kou PM. Drug-in-adhesive matrix formulation of transdermal drug delivery systems. Medical Plastics Expo, Bangkok, Thailand, 2016.

Kou PM. Transdermal drug delivery systems. Invited lecture at City University of Hong Kong, Hong Kong, China, 2016.

Kou PM, Sinenian N. Technical Analysis in Patent Litigation. American Chamber of Commerce IP Committee, Hong Kong, China, 2015.

Kou PM. PEEK: a structure-property-performance overview. Implantable Medical Device Regulation and Technology Symposium, Beijing, China, 2014. (In Mandarin Chinese)

Kou PM, Pallassana N, Cunningham B, Kohn J, Babensee JE. Elucidation of dendritic cell response-biomaterial property relationships using polymethacrylates with varied material properties. Georgia Life Sciences Summit, Atlanta, GA, 2010.

Kou PM, Pallassana N, Cunningham B, Kohn J, Babensee JE. Elucidation of dendritic cell response-biomaterial property relationships using polymethacrylates with varied material properties. Industrial Partners Symposium, Atlanta, GA, 2010.

Kou PM, Pallassana N, Cunningham B, Kohn J, Babensee JE. Elucidation of dendritic cell response-biomaterial property relationships using polymethacrylates with varied material properties. Biointerface, Atlanta, GA, 2010.

Kou PM, Joy A, Cunningham B, Kohn J, Babensee JE. Dendritic cell response to a library of terpolymers with graded variations in material properties. Biomedical Engineering Society Annual Fall Meeting, Austin, TX, 2010.

Kou PM, Schwartz Z, Boyan BD, Babensee JE. Dendritic cell response to the roughness and chemistry of titanium surfaces. Society for Biomaterials Annual Meeting, Seattle, WA, 2010.

Kou PM, Pallassana N, Cunningham B, Kohn J, Babensee JE. Dendritic cell responses to a library of polymethacrylates with varied material properties. Society for Biomaterials Annual Meeting, Seattle, WA, 2010.

Hotaling N, Kou PM, Song X, Smith D, Cummings R, Babensee JE. Dendritic cell response to surfaces presenting defined glycans. Society for Biomaterials Annual Meeting, Seattle, WA, 2010.

Hotaling N, Kou PM, Shankar S, Song Z, Smith D, Cummings R, Babensee JE. Denritic cells responses to glycan arrays. Industrial Partners Symposium, Atlanta, GA, 2009.

Kou PM and Babensee JE. A high throughput methodology to study dendritic cell/biomaterial interactions. Biomedical Engineering Society Annual Fall Meeting, St. Louis, MO, 2008.

Prior Experience

Research Assistant, Department of Biomedical Engineering, Georgia Institute of Technology, 2005–2011

Visiting Scholar, Tissue Regeneration, University of Twente, Netherlands, 2009.

Professional Affiliations

Society for Biomaterials—SFB

Biomedical Engineering Society—BMES

Society of Women Engineers—SWE

News & Events

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Bioengineering, Georgia Institute of Technology (Georgia Tech), 2011
  • B.S., Biological and Environmental Engineering, Cornell University, 2005, magna cum laude
  • Nerem Travel Award for International Collaboration, Georgia Institute of Technology, 2008

    International Student Scholarship, Cornell University, 2003–2005

    Undergraduate Research Award, Cornell University, 2004–2005

    Undergraduate Achievement Award, American Chemical Society, 2003

LICENSES & CERTIFICATIONS

ISO 13485 Medical Device Quality Management Systems Internal Auditor

PADI Advanced Open Water Diver

PADI Enriched Air Diver

LANGUAGES

  • Cantonese Chinese
  • Mandarin Chinese