Sol M. Bobst, Ph.D.

Dr. Bobst has over 5 years experience in toxicology, consulting, and chemical safety. His experience includes pharmacokinetics of drug metabolism, regulatory compliance, PBPK modeling, QSAR techniques, environmental assessments, adverse health claims in civil tort cases, risk assessments, and exposure assessments including PCB/PAHs, petroleum and petrochemical products, hydrogen sulfide, heavy metals, mold, and asbestos.

Dr. Bobst’s expertise is in the pharmacokinetics of environmental pollutants and drug metabolism. He is highly knowledgeable on the new REACH-EU chemical regulations, as well as other chemical regulatory rules. Dr. Bobst served for 3 years on the chemical safety committee at the University of Texas-Houston.

Bobst S. Legal strategies for assessing claims against Ortho Evra and venous thromboembolism. Mealey’s Publications, September 2006.

Bobst, S, Randić, M, Novič M, Vračko M. On numerical characterization of proteomic data. V: Graovac, Ante (ur.), Pokrić, Biserka (ur.), Smrečki, Vilko (ur.). In: Program and Book of Abstracts. The 21st Dubrovnik International Course & Conference on the Interfaces among Mathematics, Chemistry and Computer Sciences, MATH/CHEM/COMP 2006, Ruđer Bošković Institute, Dubrovnik, Zagreb, June 19–24, 2006.

Bobst S. Lead fumes and analysis of exposure tort claims. HarrisMartin Publishing, May–June, 2006.

Bobst S. Asbestos and specific causation. Asbestos Litigation, Mealey’s (Lexis-Nexis Publications), March 2006.

Bobst S. Toxic mold as a misnomer. Mold Litigation, HarrisMartin Publishing, December 2005.

Bobst S. Liquid wrench and benzene exposure. Benzene Litigation, HarrisMartin Publishing, October 2005.

Bobst SM, Day MC, Gilstrap LC 3rd, Xia Y, Kellems RE. Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretion. Am J Hypertens 2005; 18(3):330–336.

Bobst S. Symptoms v. pathology: Manganism and Parkinson’s disease. Litigation Watch: Welding Rods, HarrisMartin Publishing, August 2004.

Bobst S. n-Hexane and peripheral neuropathy. Toxic Tort Watch: Pesticides, Solvents, and Fumes. HarrisMartin Publishing, 2004; 1(5):2–3,6.

Bobst S. An analysis of androstenedione. Columns: Drugs and Supplements. HarrisMartin Publishing, 2004; 3(4):2-3,67.

Bobst S. An analysis of green tea extract. Columns: Drugs and Supplements. HarrisMartin Publishing, 2004; 3(3):2-3, 67.

Bobst S. An analysis of bitter orange extract. Columns: Drugs and Supplements. HarrisMartin Publishing, 2004; 3(2):2-3, 65.

Xia Y, Wen H, Bobst S, Day MC, Kellems RE. Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human trophoblast cells. J Soc Gynecol Investig 2003; 10(2):82–93.

Randić M., Gu X, Bobst S. Use of path matrices for a characterization of molecular structures. DIMACS Series in Discrete Mathematics and Computer Science 2000. 51:305–322.

Presentations

Bobst S. So you have a positive drug test, now what? DRI Trucking Law Teleconference, January 22, 2008.

Bobst S. Emerging issues in industrial hygiene: The impact of biomonitoring data. Gulf Coast Section of the American Industrial Hygiene Association, September 2007.

Bobst S. Application of graph theory to 2D proteomic gels. XXII Southwest Theoretical Chemistry Conference, Austin, TX, November 2006.

Bobst S. Application of Graph Theory to 2D Proteomic gels. National Institute of Chemistry, Ljubljana, Slovenia, August 2006.

Bobst S. Risk assessment and Seveso II compliance. Chimcomplect Engineering and Ministry of Water and Environment, Sofia, Bulgaria, June 2006.

Bobst S. CLE Workshop on toxicology: Drugs, tort and environmental. 6-Hour CLE Course, State Bar of New Mexico, March 2006.

Bobst S. Benzene and specific causation. Booth presentation at Harris Martin Benzene 101 Conference, San Antonio, TX, February 2006.

Bobst S. Hydrogen sulfide and sulfide dioxide: Toxicology and offshore safety. Amec-Paragon – Chevron, January 2006.

Bobst S. Real world toxicology. National Institute of Chemistry, Ljubljana, Slovenia, September 2005.

Bobst S. Real world toxicology: Cocaine, marijuana, and alcohol. Criminal Defense Section, Houston Bar Association, Houston, TX, April 21, 2005.

Bobst S, Zheng N, Thomas B. Real world toxicology: A framework for evaluating tort claims. Poster Presentation, Society of Toxicology, New Orleans, LA, March 2005.

Bobst S, Vracko M, Novic M, Randic M. Application of NN to proteomic data. Southwest Theoretical Chemistry Conference, Galveston, TX, October 2004.

Bobst S. Kosmata! Forensic issues: Cocaine in hair. National Institute of Chemistry, Ljubljana, Slovenia, September 2004.

Bobst S. Drug testing and Daubert. Criminal Defense Section, Houston Bar Association, Houston, TX, August 2004.

Bobst S. Bradford-Hill and specific causation. North Harris County Bar Association, May 2004.

Bobst S, Zheng N, Thomas B. Effective testimony: Five key points. Paper presented at the Southwestern Association of Toxicology, Austin, TX, November 2003.

Bobst S, Randić M. The characterization of molecular branching and helices using distance/distance matrices. Poster Presentation, 3rd Indo-U.S. Workshop on Mathematical Chemistry: with Applications to Drug Discovery, Environmental Toxicology, Cheminformatics and Bioinformatics, Duluth, MN, August 2–7, 2003.

Bobst S. Maternal autoantibodies from preeclamptic patients activate angiotensin receptors in neonatal rat cardiomyocytes. Poster Presentation, FASEB Summer Research Conference on Autoimmunity, Saxton’s River, VT, 2001.

• Independent Contractor, PSRG Inc., 2005–2007
• Visiting Research Scientist, National Institute of Chemistry, Ljubljana, Slovenia, 2004–present
• Principal, CERATOX Consulting, 2002
• Graduate Research Assistant, University of Texas, 1997–2003
• Molecular Topology Research, Department of Mathematics and Computer Science Drake University, 1996–1997
• Summer Undergraduate Research Fellowship, Department of Biology, University of Idaho, 1996
• Summer Undergraduate Research Fellowship, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, 1995
• Research Associate, Department of Chemistry, Drake University, 1994–1995
• Research Associate, Maize transformation and Elite Transformation Labs, Pioneer Hi-Bred International Inc., 1994
• Microbiology Preparations Crew, Department of Biology, Drake University, 1993–1994
  

Evaluated drug evidence in an investigation involving three different laboratory tests with different results on the same sample. Evidence was reviewed for validity of the analytical technique and relevance with respect to the drug pharmacokinetics and circumstances of the incident.

Directed an evidence investigation of a residence with a clandestine methamphetamine lab using the red phosphorous method. Chemical evidence and the ventilation of the home was assessed for odor thresholds and dispersion of phosphine gas, acetone, and methamphetamine. Analytical testing data was reviewed for method validity and accuracy for describing the contamination levels of methamphetamine in the residence.

Evaluated drug evidence for an accident investigation involving alcohol. Pharmacokinetic methods were used to determine the level of intoxication at the time of the accident.

Supervised a risk assessment of offshore drilling mud waste for a client in the offshore oil industry. The project addressed bioavailability of Soluble Barium and Zinc. The project also involved working with the State of Louisiana to change the criteria of statewide order 29B.

Supervised a risk assessment for oil well pit closures. The assessment involved reviewing data validity for site specific testing, and consideration of bioavailability of chemicals such as arsenic and benzene. The project also involved preparing comments regarding the proposed closure standards.

Participated in the review and risk management of isofluorene in a laboratory setting. Work was conducted in a committee environment. Exposure scenarios were considered on an individual, chemical specific basis. The use of isofluorene by a pregnant woman working with a fume hood was assessed for reproductive toxicity. Risk management procedures were added to the MSDS file.

• Society of Toxicology
• American Chemical Society