John Foster, Kharmen Billimoria, Maria Estela del Castillo, Stanislav Stekopytov, Heidi Goenaga-Infante and Timothy Morley. Accumulation of molybdenum in major organs following repeated oral administration of bis-choline tetrathiomolybdate in the Sprague Dawley rat. Journal of Applied Toxicology May 2022 (in Press)
Karl Heinz Weiss, Catherine Thompson, Peter Dogterom, Yi-Jin Chiou, Tim Morley, Brinley Jackson, Naseem Amin, Camille Omar Farouk Kamlin. Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects Eur J Drug Metab Pharmacokinet. 2021 Sep;46(5):665-675.
M. Estela del Castillo-Busto, Susana Cuello-Nunez, Christian Ward-Deitrich, Tim Morley and Heidi Goenaga-Infante. A fit-for-purpose copper speciation method for the determination of 1 exchangeable copper relevant to Wilson's disease. Analytical and Bioanalytical Chemistry. (June 2021)
SVETLANA V. DOBRITSA, IOK TENG KUOK, HAI NGUYEN, JEFFREY WEBSTER, ANDREW MEARNS SPRAGG, TIMOTHY MORLEY, and GRANT J. CARR. Development of a High-Throughput Cell-Based Assay for Identification of IL-17 Inhibitors. Journal of Biomolecular Screening (Volume 18 Issue 1 January 2013 pp. 74 - 83).
Zhicai Yang, Xiaomin Jin, Michael Guaciaro, Bruce F. Molino, Ursula Mocek, and Tim Morley. The Revised Structure, Total Synthesis, and Absolute Configuration of Streptophenazine A. Organic Letters. American Chemical Society. September 29, 2011
Morley, T. J.; Goodwin, D. A.; Read, N. G.; Hodgson, S. T.; Hawksworth, G. M. (1997). Mechanisms of renal glomerular toxicity of an N-hydroxyurea 5-lipoxygenase inhibitor. Human & Experimental Toxicology. Vol. 16, No. 7, pp. 412.
Morley T J; Evans G O; Goodwin D A; Read N G; Hodgson S T; Hawksworth G M. Structure-activity relationship for two lipoxygenase inhibitors and their potential for inducing nephrotic syndrome. Toxicology and Applied Pharmacology. (1997 Oct), 146 (2), 299-308.
Morley T J; Dickins M. (1990). A Study to investigate the cytotoxicity of the neuromuscular blocking agent Atracurium using primary rat hepatocyte culture. Human & Experimental Toxicology. Vol 9 (5), 345-346.
Parsons, Derrick N.; Dickins, Maurice; Morley, Timothy J. (1995). Lamotrigine: Absorption, distribution, and excretion. Antiepileptic drugs, Fourth edition. pp. 877-881. Levy, R. H.; Mattson, R. H.; Meldrum, B. S. [Eds].
Dickins, Maurice; Sawyer, David A.; Morley, Timothy J.; Parsons, Derrick N. (1995) Lamotrigine: Chemistry and biotransformation. Antiepileptic drugs, Fourth edition. pp. 871-875. Levy, R. H.; Mattson, R. H.; Meldrum, B. S. [Eds].
Presentations
Kharmen Billimoria, Timothy Morley, Maria Estela del Castillo, Stanislav Stekopytov, Heidi Goenaga-Infante, John Foster. Accumulation of molybdenum in major organs following chronic oral administration of bischoline tetrathiomolybdate in Sprague Dawley rats. EASL Conference April 2022.
S. McDougall and T. Morley. Defining the range of healthy volunteer non ceruloplasmin copper using a new copper protein speciation assay. 14th European Bioanalytical Forum. Barcelona. Nov 2021.
Wilson's Webinar Orphalan. 16th September 2021. Recent developments in Wilson's Disease Management and Follow Up. "Non Ceruloplasmin Bound Copper: The development of a reliable and precise biomarker for monitoring Wilson's Disease Patients" Dr Tim Morley PhD FRCPath. Chief Scientific Officer, Orphalan. London, UK "Recent Clinical Development in Wilson's Disease: the awaited evidence" Professor David Cassiman Hospital and University of Leuven. Leuven, Belgium
T. MORLEY, H. GOENAGA-INFANTE, E. DEL CASTILLO, S. MCDOUGALL, K. D'HOLLANDER, and O. KAMLIN. Novel Copper Protein Speciation method for calculating Serum Non Ceruloplasmin Copper: A Comparative Analysis. EASL Conference August 2021.
T. MORLEY, H. GOENAGA-INFANTE, E. DEL CASTILLO, S. MCDOUGALL, K. D'HOLLANDER, and O. KAMLIN. Defining the range of healthy volunteer Non Ceruloplasmin Copper using a new Copper Protein Speciation assay. EASL Conference August 2021.
Aurelia Poujois, Tim Morley, Catherine Thompson. Comparative Pharmacokinetic profile of two distinct trientine salt formulations used for treatment of Wilson's disease. Foundation Rothchild Paris France March 2021.
Karl Heinz Weiss, Tim Morley, Catherine Thompson. Comparative Pharmacokinetic profile of two distinct trientine salt formulations used for treatment of Wilson's disease. EASL Conference August 2020.
Tim Morley. Exploring the Chemical Characterisation risk assessment approach and complying with ISO-10993-18Informa's Life Science's 7th Biocompatibility Testing and Evaluations for Medical Devices. Dublin Ireland 2015.