Hossein Ahmadzadeh

Hossein Ahmadzadeh, Ph.D.

Associate
Mechanical Engineering
Menlo Park

Dr. Ahmadzadeh specializes in solid mechanics, failure and damage analysis, and characterization of materials. He is experienced in developing analytical and computational models for a diverse range of materials with linear elastic, non-linear hyperelastic, viscoelastic, and poroelastic behaviors, with specific application to biomedical systems. He has experience in utilizing Finite Element Analysis (FEA) tools to determine the initiation and propagation of cracks in non-linear materials, and failure and rupture of composite structures. He expertly leverages mechanical testing techniques for measurement of stress and strain, relaxation and creep, fracture toughness, and ultimate strength to inform his numerical simulations.

Prior to joining Exponent, Dr. Ahmadzadeh’s doctoral and postdoctoral research focused on creating computational models of biomechanical structures to understand the link between their composition, performance, and ultimate failure. By creating smoothed particle hydrodynamics simulations and considering large deformations, his postdoctoral research modeled crack initiation and propagation in soft tissues under different loading conditions. Similarly, his Ph.D. thesis focused on using FEA to model the response of fiber-reinforced composite structure within soft tissues to static and dynamic loadings. His numerical models have found application in determining the critical velocity of accidents causing rupture and tear in the brain, and predicting the relationship between elevated blood pressures and defect and damage propagation in blood vessels.

At the University of Pennsylvania, Dr. Ahmadzadeh served as a teaching assistant for the Mechanics of Materials class for multiple semesters. During the course, he instructed students to use COMSOL and create multiphysics models by combining structural mechanics, heat transfer, fluid mechanics, and chemical transport modules. Project examples include joule heating, phase field modeling, cohesive zone modeling, multi-phase mixing and coarsening, and design optimization.

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Materials Science and Engineering, University of Pennsylvania, 2017
  • M.S., Structural Engineering, Sharif University of Technology, Iran, 2011
  • B.S., Civil Engineering, Sharif University of Technology, Iran, 2009

Publications

Ahmadzadeh H, Rausch MK, Humphrey JD. Particle-based computational modelling of arterial disease. Journal of The Royal Society Interface 2018; 15: 20180616.

Ahmadzadeh H, Webster MR, Behera R, Valencia AMJ, Wirtz D, Weeraratna AT, Shenoy VB. Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion. Proceedings of the National Academy of Sciences 2017; 114: E1617-E1626.

Ahmadzadeh H, Smith DH, Shenoy VB. Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury. Biophysical Journal 2015; 109: 2328–2337.

Ahmadzadeh H, Smith DH, Shenoy VB. Viscoelasticity of tau proteins leads to strain rate-dependent breaking of microtubules during axonal stretch injury: predictions from a mathematical model. Biophysical Journal 2014; 106: 1123-1133.

Ahmadzadeh H, Freedman BR, Connizzo BK, Soslowsky LJ, Shenoy VB. Micromechanical poroelastic finite element and shear-lag models of tendon predict large strain dependent Poisson’s ratios and fluid expulsion under tensile loading. Acta Biomaterialia 2015; 22: 83-91.

Hossein Ahmadzadeh, Benjamin R. Freedman, Brianne K. Connizzo, Louis J. Soslowsky, Vivek B. Shenoy. Determining the contribution of glycosaminoglycans to tendon mechanical properties with a modified shear-lag model, Journal of Biomechanics 2013; 46: 2497-2503.

Presentations

Ahmadzadeh H, Rausch MK, Humphrey JD. Glycosaminoglycans in Aortic Dissection: A Model-Based Study Using Damage-based Smoothed Particle Hydrodynamics. Podium presentation, 13th World Congress on Computational Mechanics, New York, NY, 2018.

Ahmadzadeh H, Webster MR, Behera R, Valencia AMJ, Wirtz D, Weeraratna AT, Shenoy VB. A Chemo-Mechanical Computational Model for Cancer Cell Invasion in Stroma. Podium presentation, Biomedical engineering society annual meeting, Minneapolis, MN, 2016.

Ahmadzadeh H, Smith DH, Shenoy VB, Mechanical effects of dynamic binding between tau proteins on axonal microtubules during traumatic brain injury: predictions from a computational model. Podium presentation, Biomedical engineering society annual meeting, Tampa, FL, 2015.

Prior Experience

Yale University, Department of Biomedical Engineering, Postdoctoral Fellow, 2017-2019

Additional Information

Peer Reviewer

Journal of Biomechanics; Journal of The Royal Society Interface

Biophysical Journal; Biomechanics and Modeling in Mechanobiology

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Materials Science and Engineering, University of Pennsylvania, 2017
  • M.S., Structural Engineering, Sharif University of Technology, Iran, 2011
  • B.S., Civil Engineering, Sharif University of Technology, Iran, 2009