Sydney Gladman
A. Sydney Gladman, Ph.D.
Senior Associate
Polymer Science & Materials Chemistry
Natick

Dr. Gladman's research interests include the intersection of the formulation, processing, properties, and performance of polymeric materials used in traditional plastics manufacturing methods as well as additive manufacturing processes such as 3D printing. At Exponent, Dr. Gladman assists clients in a variety of industries and applications including consumer products, medical devices, textiles, military/aerospace, and the sustainability sectors. She routinely consults in the areas of failure analysis, materials selection and characterization, formulation and process development, as well as patent analysis. Dr. Gladman also has significant experience in the synthesis of autonomous and biomimetic materials such as 4D-printed programmable shape-changing polymers, 3D-printed human tissue constructs, and self-healing composite materials.

Dr. Gladman has considerable experience in the processing and formulation of polymers, hydrogels, and composites. She has extensive experience with traditional manufacturing methods such as injection molding and blow molding, as well as emerging manufacturing methods such as 3D printing. Dr. Gladman has experience in the design of novel 3D printed "ink" formulations, mammalian cell culture and tissue engineering techniques, and microencapsulation of solvents and polymers. She is also familiar with a variety of polymer characterization techniques including rheological characterization, mechanical characterization including tensile tests, fracture tests, and dynamic mechanical analysis (DMA), thermal characterization including thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC), imaging including optical, confocal, and scanning electron microscopy (SEM), and spectroscopy including infrared (IR) and ultraviolet-visible (UV-Vis).

As a graduate researcher at the University of Illinois at Urbana-Champaign in the Autonomous Materials Systems group, Dr. Gladman developed a novel microcapsule-based self-healing method to repair fracture damage in acrylic bone cement, a thermoplastic biomaterial utilized in joint replacement surgeries. She continued her academic career at Harvard University as a graduate and postdoctoral researcher with a focus on patent-pending 3D/4D printed shape-changing hydrogel composites for "smart" materials systems and 3D bioprinting of vascularized human tissue. Dr. Gladman's innovative research in 4D printing has enabled shape changing behavior in a variety of fiber-reinforced acrylamide ink formulations, with the resulting programmable transformation triggered by water, heat, or light.

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Engineering Sciences, Harvard University, 2016
  • B.S., Materials Science and Engineering, University of Florida, 2010, magna cum laude
  • Gordon Research Conference Travel Award, 2016

    Materials Research Society Best Poster: Symposium B, 2014

    Hamer Fellowship Graduate Researcher, University of Illinois at Urbana-Champaign, Materials Science and Engineering Department, 2010-2012

    Vladimir Grodsky Memorial Scholarship, Materials Science and Engineering, UF, 2007-2009

    Bright Future’s Scholarship, State of Florida, 2006-2010

Publications

Van Rees, W.M, Matsumoto, E.A., Gladman, A.S., Lewis, J.A., and Mahadevan, L. Mechanics of biomimetic 4D printed structures. Soft Matter 2018; Advance Article.

Siqueria, G., Kokkinis, D., Libanori, R. Hausmann, M.K., Gladman, A.S., Neels, A., Tingaut, P, Zimmermann, T., Lewis, J.A., and Studart, A.R. Cellulose Nanocrystal Inks for 3D Printing of Textured Cellular Architectures. Advanced Functional Materials 2017; 27: 1604619.

McCracken, J.M., Badea, A., Kandel, M.E., Gladman, A.S., Wetzel, D.J., Popescu, G., Lewis, J.A., and Nuzzo, R.G. Programming mechanical and physicochemical properties of 3D hydrogel cellular microcultures via direct ink writing. Advanced Heathcare Materials 2016; 5:1025-1039.

Gladman, A.S., Matsumoto, E.A., Nuzzo, R.G., Mahadevan, L., and Lewis, J.A. Biomimetic 4D Printing. Nature Materials 2016; 15:413–418.

Gladman, A.S., Celestine, A.N., Sottos, N.R., and White, S.R. Autonomic healing of acrylic bone cement. Advanced Healthcare Materials 2015; 4:202–207.

Kolesky, D.B., Truby, R.L., Gladman, A.S., Busbee, T.A., Homan, K.A., and Lewis, J.A. 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs. Advanced Materials 2010; 26:3124–3130.

Presentations

Gladman, A.S. Biomimetic 4D printing. Gordon Research Conference: Multifunctional Materials Structures, Ventura, CA, 2016.

Gladman, A.S. Biomimetic 4D printing. Materials Research Society Conference, Boston, MA, 2015.

Gladman, A.S. 4D printing of nanocomposite hydrogel architectures. Materials Research Society Conference, Boston, MA, 2014.

Gladman, A.S. Autonomic healing of acrylic bone cement. Soft Materials Seminar, UIUC, 2012.

Gladman, A.S. Autonomic healing of acrylic bone cement. Materials Research Society Conference, Boston, MA, 2011.

Gladman, A.S. Self-healing of acrylic bone cement. 48th Annual Technical Meeting of the Society of Engineering Sciences, Evanston, IL, 2011.

Patents

Provisional Patent Application 62260981: Hydrogel composite ink formulation and method of 4D printing a hydrogel composite structure, 2015 (Lewis, J.A., Gladman AS, Matsumoto, E.A., Mahadevan, L., and Rittner, M.N.).

Non-Provisional Patent Application 14954228: Method of 4D printing a hydrogel composite structure, 2015 (Lewis, J.A., Gladman AS, and Rittner, M.N.).

International Patent Application Number PCT/US2014/063810: Method of printing a tissue construct with embedded vasculature, 2014 (Lewis, J.A., Kolesky, D.B, Scott, M.A., Homan, K.A., Truby, R.L., Gladman AS, and Rittner, M.N.).

Professional Affiliations

Materials Research Society

Society of Plastics Engineers

ANTEC New Technology Forum Committee Member

Knowledge

News & Events

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Engineering Sciences, Harvard University, 2016
  • B.S., Materials Science and Engineering, University of Florida, 2010, magna cum laude
  • Gordon Research Conference Travel Award, 2016

    Materials Research Society Best Poster: Symposium B, 2014

    Hamer Fellowship Graduate Researcher, University of Illinois at Urbana-Champaign, Materials Science and Engineering Department, 2010-2012

    Vladimir Grodsky Memorial Scholarship, Materials Science and Engineering, UF, 2007-2009

    Bright Future’s Scholarship, State of Florida, 2006-2010