Maria Pellizzaro
Maria L. Pellizzaro, Ph.D.
Senior Scientist
Chemical Regulation & Food Safety
Harrogate (UK)

Dr. Pellizzaro is responsible for: the conduct of human health exposure assessments for pesticides, biocides, and industrial chemicals; compiling toxicology sections of dossiers for regulatory submission; and the toxicological analysis of molecules using the OECD toolbox.

After completing a Ph.D. in organic chemistry, which involved the synthesis of small molecules and NMR analysis of their intermolecular interactions, Dr. Pellizzaro worked at Lhasa Limited which develops QSAR software. Whilst at Lhasa she specialized in writing structural alerts for various toxicological endpoints, including skin sensitization and mutagenicity. She also gained experience in in vitro dermal absorption studies.

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Chemistry, University of Leeds, UK, 2012
  • MChem., Chemistry with Medicinal Chemistry, University of Leeds, UK, 2008

Publications

Pellizzaro ML, Covey-Crump EM, Fisher J, Werner ALD, Williams RV. Investigating a relationship between the mutagenicity of arylboronic acids and 11B NMR chemical shifts. Chemical Research in Toxicology 2015; 28:1422–1426. doi: 10.1021/acs.chemrestox.5b00078.

Pellizzaro ML, Houton K, Wilson AJ. Sequential and phototriggered supramolecular self-sorting cascades using hydrogen-bonded motifs. Chemical Science 2013; 4:1825–1829. doi 10.1039/C3SC22194F.

Pellizzaro ML, Fisher J, Wilson AJ. Electronic substituent effects on hydrogen-bonding motifs modulate supramolecular polymerization. Royal Society of Chemistry Advances, 2013; 3:3103–3108. doi 10.1039/c2ra22715k.

Pellizzaro ML, Barrett SA, Fisher J, Wilson AJ. Design, synthesis and binding studies of a novel quadruple ADDA hydrogen-bond array. Organic & Biomolecular Chemistry 2012; 10:4899–4906. doi: 10.1039/C2OB25333J.

Pellizzaro ML. Development of building blocks exhibiting self-sorting molecular recognition properties: Towards coded self-assembly processes. Ph.D. Thesis, University of Leeds, January 2012. http://etheses.whiterose.ac.uk/2281/.

Pellizzaro ML, McGhee AM, Renton LC, Nix MG, Turnbull WB, Fisher J, Wilson AJ. Conformer independent ureidoimidazole motifs - tools to probe conformational and tautomeric effects on the molecular recognition of triply hydrogen-bonded heterodimers. Chemistry - A European Journal 2011; 17:14508–14517. doi: 10.1002/chem.201102128.

Gooch A, McGhee AM, Pellizzaro ML, Lindsay CI, Wilson AJ. Substituent control over dimerization affinity of triply hydrogen bonded heterodimers. Organic Letters 2011; 13:240–243. doi: 10.1021/ol102619u.

Prior Experience

Scientist, Lhasa Limited, 2012–2015

Knowledge

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Chemistry, University of Leeds, UK, 2012
  • MChem., Chemistry with Medicinal Chemistry, University of Leeds, UK, 2008