Cristina Rodriguez-Quijada specializes in the assessment of materials used throughout the pharmaceutical and medical device fields. She supports clients in the design and development of diagnostic and therapeutic systems, by researching the interface between biology and materials. She has expertise identifying and characterizing proteins, bacteria and viruses from diverse biological fluids and biomaterial surfaces with biochemical techniques.
Cristina Rodriguez-Quijada has a broad experience using conventional bioassays such as immunoassays (ELISA, Western blot, immunochromatographic assays), proteomic assays (LC-MS, SDS-PAGE), cell culture, flow cytometry and microbiology techniques. She routinely utilizes imaging techniques such as SEM, TEM, fluorescence microscopy and confocal imaging to assess the performance of theranostic systems. She is skilled in nanoparticle characterization techniques such as dynamic light scattering and zeta potential. In addition, she has considerable experience with a variety of spectroscopic techniques including UV-Vis, Raman and Nuclear Magnetic Resonance (NMR) as well as material characterization techniques including Gel Permeation Chromatography (GPC), mechanical testing and rheometry.
Prior to joining exponent, Cristina Rodriguez-Quijada completed her Ph.D. work in Biomedical Engineering and Biotechnology at the University of Massachusetts Boston, which is currently awaiting conferral. Her dissertation focused on the study of the interactions between inorganic materials and biomolecules to enhance the performance and capabilities of biomaterials used as therapeutic or diagnostic tools. Cristina Rodriguez-Quijada has been awarded multiple fellowships and awards from private and public entities that supported her undergraduate and graduate work. She is an author on multiple peer-reviewed publications and has shared her research interests at several international and domestic conferences.
CREDENTIALS & PROFESSIONAL HONORS
- M.S., Bioengineering, Universitat Ramon Llull (IQS School of Engineering), 2016
- B.S., Chemical Engineering, Universitat Ramon Llull (IQS School of Engineering), 2014
Rodriguez-Quijada C, de Puig H, Sánchez-Purrà M, Yelleswarapu C, Evans J, Celli J, Hamad-Schifferli K. Protease Degradation of Protein Coronas and its Impact on Cancer Cells and Drug Payload Release. ACS Applied Materials and Interfaces 2019; 11, 16, 14588-14596.
Russo L, Sánchez-Purrà M, Rodriguez-Quijada C, Leonardo B, Puntes V, Hamad-Schifferli K. Detection of Resistance Protein A (MxA) in Paper-based Immunoassays with Surface Enhanced Raman Spectroscopy with AuAg Nanoshells. Nanoscale 2019; 11, 10819-10827.
Hristov D, Rodriguez-Quijada C, Gomez-Marquez J, Hamad-Schifferli K. Designing Paper-based Assays for Biomedical Applications. Sensors 2019; 19, E554.
Sánchez-Purrà M, Roig-Solvas B, Rodriguez-Quijada C, Leonardo B, Hamad-Schifferli K. Reporter Selection for Nanotags in Multiplexed Surface Enhanced Raman Spectroscopy Assays. ACS omega 2018; 3, 9, 10733-10742.
Rodriguez-Quijada C,† Sánchez-Purrà M,† de Puig H, Hamad-Schifferli K. Physical Properties of Biomolecules at the Nanomaterial Interface. Journal of Physical Chemistry 2018; 122, 11, 2827-2840.
Rodriguez-Quijada C, Hamad-Schifferli K. Applications of Plasmonic Nanomaterials for Phototriggered Theranostics. Handbook of Nanomaterials for Cancer Theranostics 2018; Chapter 5, 125-142.
Sánchez-Purrà M, Roig-Solvas B, Versiani A, Rodriguez-Quijada C, de Puig H, Bosch I, Gehrke L, Hamad-Schifferli K. Design of SERS Nanotags for Multiplexed Lateral Flow Immunoassays. Molecular Systems Design & Engineering 2017; 2, 401-409.
Rodriguez-Quijada C, Hamad-Schifferli K. Using Gold Nanoparticles for Diagnostics and Sensing in Low Cost Devices. Oral Communication. American Chemical Society National Meeting (ACS), San Diego, CA, 2019.
Rodriguez-Quijada C, Hamad-Schifferli K. Rapid Paper Tests for Detection of Pathogenic Vibrios in Aquaculture. Oral Communication. American Chemical Society National Meeting (ACS), San Diego, CA, 2019.
Rodriguez-Quijada C, Shiaris M, Tlusty M, Hamad-Schifferli K. Vibrio parahaemolyticus (Vp) Detection with Rapid Test Immunoassays. Poster presentation. Annual Environmental Research Colloquium, Boston, MA, 2019.
Rodriguez-Quijada C, de Puig H, Sánchez-Purrà M, Yelleswarapu C, Celli J, Hamad-Schifferli K. Exposure to Proteolytic Environment from Pancreatic Tumor Cells Leads to Protein Corona Degradation. Oral Communication. International Conference on Nanomedicine and Nanobiotechnology, Rome, Italy, 2018.
Rodriguez-Quijada C, de Puig H, Sanchez-Purra M, Yelleswarapu C, Celli J, Hamad-Schifferli K. Protein Corona Degrades when Exposed to the Proteolytic Environment of Pancreatic Ductal Adenocarcinoma. Oral Communication. American Chemical Society National Meeting (ACS), Boston, MA, 2018.
Rodriguez-Quijada C, de Puig H, Sánchez-Purrà M, Yelleswarapu C, Celli J, Hamad-Schifferli K. Protein Corona Degradation in Tumor Microenvironment Leads the Fate and Theranostic Efficacy of Gold Nanoparticles. Poster presentation. The Networking Exchange at the Broad Institute, Boston, MA, 2018.
Rodriguez-Quijada C, Cramer G, Petrovic L, Celli J, Hamad-Schifferli K. Protein Corona Evolution in Tumor Microenvironment Defines the Fate and Theranostic Efficacy of Nanocarriers. Oral Communication. Material Research Society (MRS) Fall, Boston, MA, 2017.
Visiting Student, Fraunhofer Center for Manufacturing Innovation, July 2015-June 2016
Undergraduate Research Assistant, Sagetis Biotech, May 2014-October 2014
Process and Project Engineer Assistant, CPQ Ingenieros, March 2014-July 2014
Undergraduate Research Assistant, Universitat Ramon Llull (IQS School of Engineering), June 2013-September 2013