Aerosolized Disinfection of Large Indoor Spaces

Exponent’s trusted advisors can help owners and operators of large indoor spaces optimize the distribution of disinfecting aerosols to protect employees and customers from COVID-19.

Disinfection particle tracks and dropliet lifetimes
Disinfectant particle tracks and droplet lifetimes for a disinfectant being sprayed in a patient waiting room

Our Expertise:

Exponent’s multi-disciplinary team of mechanical engineers and thermal scientists has analyzed complex air flows using computational fluid dynamics (CFD) techniques, including modeling the distribution of aerosolized disinfectants in indoor spaces. They have also been active in the American Society of Heating, Refrigerating, and Air-Conditioning Engineers (ASHRAE) for the operation of heating, ventilating, and air-conditioning (HVAC) systems.

For over 25 years, our microbiologists have helped in the generation of data to meet U.S. Environmental Protection Agency (EPA) and global microbiology regulations. We have registered numerous end-use antimicrobial products and assisted in writing policies and guidelines with state and federal regulators. Our team has extensive knowledge of the clinical trial and registration activities required for disinfecting aerosols and other antimicrobial products to safely come to market.

Our Capabilities:

Assessment of disinfecting aerosol distribution and efficacy in indoor spaces

Exponent’s multi-disciplinary team of mechanical engineers and microbiologists can help owners and operators of offices, gyms, movie theaters, and retailers understand how spray systems that atomize and distribute small drops of disinfectant would behave in indoor spaces. Our advisory work includes, but is not limited to:

  • CFD modeling of particle tracks and droplet lifetimes in simulated real-world conditions
  • Analysis of how droplet sizes, spray patterns, spray rates, and air currents from HVAC systems can affect disinfectant dispersal and deposition
  • Assessment of outlying results within the context of thermal fluid science fundamentals
  • Recommended application techniques and aerosol sizes to optimize disinfectant coverage in a given space

Customized guidance for disinfecting large indoor spaces

Exponent’s multi-disciplinary team of fluid mechanics experts can help clients build customized plans to effectively and efficiently disinfect their indoor spaces. Our advisory work includes, but is not limited to:

  • Evaluation of heating, ventilation, and air-conditioning patterns of air flow in a given space
  • Recommendations on location and rate of applying disinfecting aerosol spray
  • Strategies to optimize disinfecting aerosol consumption
  • Evaluation of disinfecting system efficiencies

Demonstration of disinfecting aerosol safety

Exponent’s microbiologists can help manufacturers of disinfecting aerosols give regulators and end-users confidence in the safety of their products. Our advisory work includes, but is not limited to:

  • Clinical trial support and proof of principle
  • Collaboration with governmental and competent authorities (e.g., EPA, EU Member States, etc.) for regulation and registration compliance as required
  • Navigation of EPA Emerging Viral Pathogens Guidance, List N posting, and List N registrant communication to end users

For more information on our services, please contact 888.656.EXPO (within the U.S.), 650.326.9400 (outside the U.S.), or info

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