Lijie Yang
Lijie Yang, Ph.D.
Engineer
Mechanical Engineering
Shanghai

Dr. Yang specializes in fluidic and thermal engineering, solid mechanics, biomechanics, and finite element analysis (FEA). She is familiar with system design and 3D modeling using Creo Parametric and SolidWorks across a broad scale, ranging from boiler, heat exchanger, and flash evaporation systems down to bioMEMS and microfluidics. She also has hands-on cleanroom experience with photolithography, soft lithography, thin film deposition, and etching, as well as surface characterization using atomic force microscopy (AFM), scanning electron microscopy (SEM), and Raman spectroscopy. In addition, she is knowledgeable in biological signal acquisition and immunofluorescence microscopy.

Prior to joining Exponent, Dr. Yang was a Research Assistant in the Micro/Nanoscale Thermal-Fluids Laboratory at Vanderbilt University, where she designed a collection of bioMEMS and microfluidic platforms to investigate cell mechanotransduction and electrophysiology, as well as organism behaviors. She developed a cutting-edge optoelectronic graphene transistor-based bioMEMS for probing neuronal electrical activities with ultrahigh spatiotemporal resolution using scanning photocurrent microscopy. Also, Dr. Yang studied biomechanics of cells through a novel automatic setup and mathematic modeling. In her earlier master’s program, she designed and built a high-pressure flash evaporator that allows operators to experimentally study a complex phase-change phenomenon, flash evaporation; Dr. Yang was granted a patent for the flash evaporator in 2012. She also gained extensive multiphysics finite element modeling experience during system strength validation and computational fluid dynamics (CFD) study, and she is proficient with ANSYS Fluent and COMSOL Multiphysics software.

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Mechanical Engineering, Vanderbilt University, 2017
  • M.S., Mechanical Engineering, Harbin Engineering University, 2012
  • B.S., Mechanical Engineering, Harbin Engineering University, 2009
  • Vanderbilt University Graduate Student Scholarship

    Outstanding Dissertation Award, 2009

    Outstanding Graduate Award, 2009

    National Scholarship, 2008

LANGUAGES

  • Mandarin

Publications

Yang L, Carrington LJ, Erdogan B, Ao M, Brewer BM, Webb DJ, Li D. Biomechanics of cell reorientation in a three-dimensional matrix under compression. Experimental Cell Research 2017; 350(1):253-266.

Yang L, Hong T, Zhang Y, Arriola JGS, Nelms BL, Mu R, Li D. A microfluidic diode for sorting and immobilization of Caenorhabditis elegans. Biomedical Microdevices 2017; 19(2):38.

Ao M, Brewer BM, Yang L, Franco Coronel OE, Hayward SW, Webb DJ, Li D. Stretching fibroblasts remodels the extracellular matrix and alters cancer cell migration. Scientific Reports 2015; 5:8334.

Jean L, Yang L, Majumdar D, Gao Y, Shi M, Brewer BM, Li D, Webb DJ. The rho family GEF Asef2 regulates cell migration in three dimensional (3D) collagen matrices through myosin II. Cell Adhesion and Migration 2014; 8(5):460–467.

Brown JA, Sherrod SD, Goodwin CR, Brewer BM, Yang L, Garbett KA, Li D, McLean JA, Wikswo JP, Mirnics K. Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia. Journal of Neuroinflammation 2014; 11(1):183.

Shao Y, Li Y, Yang L, Zhang X, Yang L, Wu H, Xu R. New experimental system for high pressure and high temperature flashing evaporation experiments. Applied Thermal Engineering 2014; 66 (1–2), 148-155.

Quan C, Later K, Yang L, Peng S, Zhang A, Hao Q, Zhang J, Sun W, Yuan L, Peng GD. FBG application in monitoring the liquid-solid and gas-liquid phase transitions of water. Proceedings of SPIE, The 3rd Asia Pacific Optical Sensors Conference 2012.

Presentations


Yang L, Carrington LJ, Wang L, Simaan N, Webb DJ, Li D. Cell response to static and cyclic compression in a three-dimensional matrix. EMI&PMC, Nashville, USA, May 2016.

Yang L, Carrington LJ, Webb DJ, Li D. Fibroblast reorientation in a three-dimensional matrix under compression. 5th ASME Micro/Nanoscale Heat & Mass Transfer International Conference, Singapore, Singapore, Jan 2016.

Yang L, Brewer BM, Ao M, Webb DJ, Li D. The effects of mechanical stress in normal tissue fibroblast activation and cancer associated fibroblast genesis. ASME 2014 International Mechanical Engineering Congress and Exposition, Montreal, Canada, November 2014.

Patents

China Patent ZL 2012 1 0011804.2: A High-Pressure Flash Evaporator, March 2014 (Yang L, Li Y, et al).

CREDENTIALS & PROFESSIONAL HONORS

  • Ph.D., Mechanical Engineering, Vanderbilt University, 2017
  • M.S., Mechanical Engineering, Harbin Engineering University, 2012
  • B.S., Mechanical Engineering, Harbin Engineering University, 2009
  • Vanderbilt University Graduate Student Scholarship

    Outstanding Dissertation Award, 2009

    Outstanding Graduate Award, 2009

    National Scholarship, 2008

LANGUAGES

  • Mandarin